If you have decided to self-publish your novel, then you have also decided to do your own marketing. That is no easy task, but with the right support and direction, many people are succeeding in the self-publishing world. For some, their self-pub success is such that they never pursue traditional publishing. For others, one great self-pubbed title can be the stepping stone to representation and a house contract.
The end of a story, as well as the beginning, exists as one arbitrary point in time for the characters who are presumably going about their day, unaware that they are about to enter or even conclude a critical and story-worthy segment of their lives. What I'm referring to is narrative plausibility.
Another thing that happens when you come back to a manuscript with fresh eyes: you spot things like thematic connections and symbols you had no idea were there. Most of this is stuff you did without even realizing it (yes, you are that smart). The trick now is to tease out these connections with a light touch, plant the seeds that need planting—and then walk away and trust your reader to get it.